Harm Reduction Issues

Overdose Prevention

Is someone overdosing right now?

Overdose deaths are preventable. We have the tools we need to stop people from dying from drugs.

190 people die from an overdose every day. That equals 70,000 avoidable deaths every year.

Harm Reduction offers evidence-based strategies that reduce the risk of dying from an overdose. We aim to support people who use drugs, and the people who love people who use drugs, with information to mitigate the risk of an overdose and to stop an overdose while it’s happening.

Credit: Nigel Brundsen

Search the Resource Library

Explore our resource library for practical resources to promote the health and dignity of people affected by drug use. You’ll find up-to-date fact sheets, webinars, manuals, training guides, and more.

Be prepared to stop an overdose

You can reverse an overdose if you know what to do and you act in time. Whether you use drugs, love someone who does, or just care about the people in your community, it’s important to be prepared if you encounter someone who is overdosing.

Overdose Trends and Tools

Two factors have radically altered the landscape for people who use drugs – one for better, one for worse.

Fentanyl is responsible for more overdoses than any other opioid.

It’s important to know what fentanyl is and how you can reduce risks of an overdose.

Not enough people have access to naloxone.

High-dose opioids are prescribed 70x more often than naloxone. Make sure the people in your community have access to this life-saving medication.


People leaving jails and prisons are at increased risk of overdose.

Start an Overdose Prevention Program

Learn the basics of overdose prevention and the history of naloxone distribution in the United States.

Online Training Institute

Looking to start an overdose prevention and naloxone distribution program? Take a look at our implementation guide.

Check out the guide

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Become a Harm Reduction Champion

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