Harm Reduction Issues

Medication for Opioid Use Disorder (MOUD)

There are many reasons that someone may be using opioids. More than 2 million people in the U.S. have an opioid use disorder (OUD) related to prescription opioids. Another quarter of a million people have an OUD related to heroin.

For people who want to reduce or stop using opioids, evidence-based approaches are available to do this safely. Medications for opioid use disorder (MOUD) are one such approach, and they’re most effective for long-term success when someone chooses to start treatment (versus being coerced or mandated).

Buprenorphine and Naloxone Sublingual Film, medication for opioid use disorder
Credit: Kim Sue

Search the Resource Library

Explore our resource library for practical resources to promote the health and dignity of people affected by drug use. You’ll find up-to-date fact sheets, webinars, manuals, training guides, and more.

Benefits of Medications for Opioid Use Disorder

This evidence-based treatment has been proven to:

Support people who to choose to reduce or stop their opioid use

Increase the likelihood that a person will continue to not use drugs

Reduce opioid use and symptoms related to opioid use disorder

Reduce the risk of infectious disease transmission

Reduce the chances of an overdose related death

For more information about this proven harm reduction strategy, read our Fact Sheet on Medications for Opioid Use Disorder.

The Gold Standard with Dr. Kim Sue

There are many ways that you can get medication for opioid use disorder into the hands of people who need it. Listen to our podcast The Gold Standard by our former Medical Director Dr. Kim Sue to learn more about innovative programs across the country.

Types of Medications for Opioid Use Disorder

There are two types of evidence-based medications used to treat opioid use disorder that we support: methadone and buprenorphine.


Credit: Kim Sue

What it is: a partial opioid agonist, meaning that it binds to those same opioid receptors but activates them less strongly than full agonists do.

How it works: reduces cravings and withdrawal symptoms without producing euphoria.

How to get it: can be prescribed by certified physicians through the Drug Addiction Treatment Act.


What it is: synthetic opioid agonist that binds to opioid receptors

How it works: eliminates withdrawal symptoms and relieves cravings

How to get it: must be dispensed through specialized opioid treatment programs

Find Buprenorphine

Harm reduction organizations around the country are working to make medications for opioid use disorder accessible to anyone who needs them.

Local harm reduction organizations and syringe service programs can help connect you with services.

Find Harm Reduction Near You

SAMHSA’s buprenorphine finder is a directory of thousands of providers around the country who are authorized to treat opioid use disorder.

Find a provider near you.

Please note that we have not vetted the providers on this list. You may want to call ahead to be sure that the information is still accurate.

Recent Wins

In 2019, National Harm Reduction Coalition partnered with ED-Bridge to expand access to buprenorphine in emergency room settings in California. Thanks to this effort, people seeking treatment for opioid use disorder can now access 24/7 treatment at 52 hospital sites on demand.

Harm Reduction Needs You. Join the Movement.

Become a Harm Reduction Champion

Get involved in your community