Credit: Luceo

Decades of experience and evidence prove that getting naloxone into the hands of people who use drugs is the most effective way to prevent overdose.

Tens of thousands of providers and programs across the country are working to support the resilience of people who use drugs.

National Harm Reduction Coalition supports the health and dignity of people who use drugs. By providing educational information around safer drug use, increasing access to the powerful antidote naloxone, and conducting hundreds of overdose prevention trainings each year, we help save thousands of lives.

Healing Takes All Hands

We focus on building power with people who use drugs to create solutions that reduce the number of overdoses in their communities. To bring these strategies to scale, we support and work with:

People who use drugs

Local community leaders

Indigenous communities and communities of color

Harm reduction organizations

Policymakers and advocates

Shelter and supportive housing agencies

Substance use treatment programs

Faith-based groups

Movement building organizations

Want to train your group in overdose prevention?

Overdose is Preventable

Over 750,000 people have died from a drug overdose in the last 20 years, many of which could have been prevented if the people using drugs had access to life-preserving tools. Overdose risk is intensified by policies that put people further into harm’s way, including policing of drug use, the housing affordability crisis, and limited access to effective drug treatment.

We focus on expanding access to evidence-based tools and information proven to help save lives.


a life-saving medication that can reverse the effects of an opioid overdose

Understand how it works

Learn how to administer it


a powerful synthetic opioid that is 50 times more potent than heroin

Understand the risks

Learn how to test for it

Bring the overdose prevention conversation & services to your community. Take the Overdose Prevention & Response training.

Help Make Naloxone Accessible

Power lies in numbers. The Harm Reduction movement relies on hundreds of organizations working together to implement evidence-based harm reduction strategies in their local communities.

Here are some key training resources to help you implement a naloxone program in your community.

Be Prepared. Save Lives.

Community members are critical responders. Know what to do in the event of an overdose.

Nationally-Renowned Overdose Prevention Program

We focus on building power with community leaders to make naloxone accessible to people who use drugs and people who love people who use drugs. Getting naloxone into the hands of people who use drugs is the single most effective way to prevent overdose in a community.

The DOPE Project, the largest single-city naloxone distribution program in the country, reduced overdose deaths in San Francisco by 2,600 in 2019.

Harm Reduction Needs You. Join the Movement.

Become a Harm Reduction Champion

Get involved in your community