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Naloxone Program Case Studies

Take-home naloxone programs have been established in approximately 200 communities throughout the United States. These vital programs expand naloxone access to drug users and their loved ones by providing comprehensive training on overdose prevention, recognition, and response (including calling 911 and rescue breathing) in addition to prescribing and dispensing naloxone.

The following case studies illustrate a variety of models for incorporating overdose prevention and survival programs, including naloxone distribution, into community programs.

Chicago Recovery Alliance

Chicago, IL:  Dan Bigg from CRA talks about how the first take-home naloxone program in the US began.

Clean Works

Grand Rapids, MI: A needle exchange program in Michigan takes action to expand access to Naloxone.

The DOPE Project

San Francisco, CA: The DOPE Project borrows from their friends, gains the support of the city public health department and secures funding and a doctor to support their existing overdose prevention work.

Harm Reduction Action Center

Denver, CO: HRAC demonstrates how a program that cannot provide take-home naloxone at this time has found creative ways to still provide overdose prevention services.

Learn To COPE Parents Group

Massachusetts: A life-saving collaboration between parents and a harm reduction program.

Massachusetts Overdose Education & Naloxone Distribution (OEND)

Massachusetts: Massachusetts creates a comprehensive statewide naloxone distribution program that is fully supported by the Department of Public Health after years of work by harm reductionists and concerned community members.

Prevention Point Pittsburgh #1

Pittsburgh, PA: Prevention Point Pittsburgh works with local physicians and pharmacists to increase the accessibility to naloxone for individuals who are legitimately prescribed opioids for pain, in addition to those who may be abusing prescription pain medications.

Prevention Point Pittsburgh # 2

Pittsburgh, PA:Taking overdose prevention into the jails to reach those at risk.

Project Lazarus

Wilkes County, NC: Project Lazarus developed a community-based overdose prevention program that focused on increasing access to naloxone for prescription opioid users by encouraging physicians to prescribe the antidote to patients at highest risk of an overdose.

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